Is zoloft activating or sedating

Selective serotonin reuptake inhibitors in affective disorders–I.

Risk of upper gastrointestinal tract bleeding associated with selective serotonin reuptake inhibitors and venlafaxine therapy.

Research Triangle Park, NC: Glaxo Smith Kline; 2008.

Research Triangle Park, NC: Glaxo Smith-Kline; 2008.

With Tranylcypromine for example a lot of people find it quite sedating.

Typically at lower doses Venlafaxine is quite sedating while above 200mg it becomes quite activating.

Duloxetine for example is a slightly stronger NRI than Venlafaxine and so tends to be more activating. So other than placing Bupropion at the top you can't really decide one is more stimulating than another.

Steps following attainment of remission: discontinuation of antidepressant therapy.

Discontinuation symptoms in users of selective serotonin reuptake inhibitors in clinical practice: tapering versus abrupt discontinuation.

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