Validating clinical trial data reporting

It has been emphasized that most pathological symptoms of autism result from altered perception of external stimuli, which arouse fear and anxiety.Currently, there are no biological markers for autism and there is no proven cure for this disorder.Prospective clinical trial registration aims to address publication and reporting bias.Unfortunately, not all clinical trials are registered before they start.

PRINTO initially included 14 European countries (about 88 countries, 628 centres worldwide with 1350 members today), with the goal to foster, facilitate and co-ordinate the development, conduct, analysis, and reporting of multi-centres, international clinical trials and/or outcome standardisation studies in children with paediatric rheumatic diseases (PRD).

According to the American Academy of Neurology (AAN)'s practice parameter, Screening and Diagnosis of Autism (Filipek et al, 2000), autism is characterized by severe deficiencies in reciprocal social interaction, verbal and non-verbal communication, and restricted interests.

It usually commences before the age of 3 years and lasts over the whole lifetime.

A pioneer of open access publishing, BMC has an evolving portfolio of high quality peer-reviewed journals including broad interest titles such as BMC Biology and BMC Medicine, specialist journals such as Malaria Journal and Microbiome, and the BMC series. We are committed to continual innovation to better support the needs of our communities, ensuring the integrity of the research we publish, and championing the benefits of open research. BMC Annual Report 2017 Elderly men across Europe and the US spend less time on housework than elderly women, according to researchers at the Leibniz Institute for Prevention Research and Epidemiology.

And while those who did more housework felt healthier, women who did long hours of housework combined with too much or too little sleep reported poorer health. Researchers tell us they want to share their data to progress research, to receive more credit and visibility for their work and to comply with funder policies.

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Current screening methods may not identify children with milder variants of autism, those without mental retardation or language delay, such as verbal individuals with high-functioning autism and Asperger’s disorder, or older children, adolescents, and young adults.

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